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<p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;; font-weight: bold;">イプラトロピウム</span> <span lang="EN-US" style="font-size: 10pt;"><font face="Century"><span style= "font-weight: bold;">ipratopium</span> (</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">アトロベント</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">Atrovent):</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">抗コリン薬</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">第四級アンモニウム</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">気管支収縮予防</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">吸入で用いられる</span> <span lang="EN-US" style="font-size: 10pt;"><font face= "Century">(</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">専用のアダプターを用いて</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">, 1</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">回</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">1-2</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">噴射</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">).</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">【適応】</span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">次の疾患の気道閉塞性障害に基づく呼吸困難など諸症状の緩解</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">気管支喘息</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">慢性気管支炎</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺気腫</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;; font-weight: bold;"><br></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;; font-weight: bold;">アルブテロール</span> <span lang="EN-US" style="font-size: 10pt; font-weight: bold;"><font face= "Century">=</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;; font-weight: bold;">サルブタモール</span> <span style="font-size: 10pt;"><font face="Century"><span lang= "EN-US"><span style="font-weight: bold;">salbutamol sulfate</span>:</span></font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">気管支拡張</span><font face="Century"><span style="font-size: 10pt;">�</span><span lang="EN-US" style="font-size: 10pt;">2-</span></font><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">刺激剤</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">【適応】錠剤・エアゾール・吸入液:次の疾患の気道閉塞性障害に基づく諸症状の緩解</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">気管支喘息</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">小児喘息</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺気腫</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">急・慢性気管支炎</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺結核</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">, [</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">錠剤は次も含む</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">]</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">ケイ肺結核</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">適応関連注意</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">[</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">エアゾール</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">]:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">喘息発作に対する対症療法剤であるので</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">本剤の使用は発作発現時に限る</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">シロップ・ドライシロップ</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">次の疾患に基づく気管支けいれんの緩解</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">気管支喘息</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">気管支炎</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">喘息様気管支炎</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">【重大な副作用】重篤な血清カリウム値の低下</span> <span lang="EN-US" style="font-size: 10pt;"><font face= "Century">(</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">頻度不明</span><font face="Century"><span lang="EN-US" style="font-size: 10pt;">):</span> <span style= "font-size: 10pt;">Beta</span><span lang="EN-US" style= "font-size: 10pt;">2-</span></font><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">刺激剤により重篤な血清カリウム値の低下が報告されている</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">また</span><font face="Century"><span lang="EN-US" style="font-size: 10pt;">,</span> <span style= "font-size: 10pt;">beta</span><span lang="EN-US" style= "font-size: 10pt;">2-</span></font><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">刺激剤による血清カリウム値の低下作用は</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">キサンチン誘導体</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">ステロイド剤及び利尿剤の併用により増強することがあるので</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">重症喘息患者では特に注意する</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">更に</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">低酸素血症は血清カリウム値の低下が心リズムに及ぼす作用を増強することがある</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">このような場合には血清カリウム値をモニターすることが望ましい</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span lang="EN-US" style= "font-size: 10pt;"><font face="Century">Definition of Shotty<br></font></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span lang="EN-US" style= "font-size: 10pt;"><font face="Century">Shotty: Resembling shot or pellets of lead, shotgun pellets and, hence, hard and round. The term "shotty" was in use in the 19th century. It is now generally obsolete but it is still in medicinal usage.<br></font></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span lang="EN-US" style= "font-size: 10pt;"><font face="Century">Shotty is very commonly used in describing the feel of lymph nodes (the lymph glands) when they are palpated (felt) through the skin. "Shotty" lymph nodes are ones that are not only hard and round but also small and surely of no consequence.<br></font></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><font face= "Century"><span lang="EN-US" style="font-size: 10pt;">No consequence is not always the case with shotty. The pustules (the little pockets of pus) in smallpox are said to feel shotty, according to D.A. Henderson, the director of the World Health Organization (WHO) Smallpox Eradication Unit from its inception in 1966 to 1977. "Smallpox pustules have a dimple, a dent in the center. Doctors say that the pustules have a 'shotty' feel, like shotgun pellets. You can roll them between your fingertips under the skin,"</span> <span lang="EN-US" style="font-size: 10pt;">Henderson</span> <span lang="EN-US" style="font-size: 10pt;">recounted (quoted by Richard Preston in The New Yorker,</span> <span lang="EN-US" style="font-size: 10pt;">July 12, 1999</span><span lang="EN-US" style="font-size: 10pt;">).<br></span></font></p> <p align="right" class="MsoNormal" style= "margin: 0mm 0mm 0pt; text-align: right;"><span lang="EN-US" style= "font-size: 10pt;"><font face="Century">[MedicineNet]<br></font></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"></p> <p class="MsoNormal"><b style=""><span style= "font-family: &quot;MS 明朝&quot;;">フルニソリド</span></b></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">副腎皮質ホルモン</span> <span style="font-family: &quot;MS 明朝&quot;;">点鼻液</span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">【適応】アレルギー性鼻炎,血管運動性鼻炎</span></p> <p class="MsoNormal"></p> <p class="MsoNormal"><b style=""><span style= "font-family: &quot;MS 明朝&quot;;">セレベント</span></b></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">キシナホ酸サルメテロール</span><span lang="EN-US">salmeterol xinafoate</span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">長時間作動型気管支拡張</span><span style="">�</span><span lang="EN-US">2-</span><span style="font-family: &quot;MS 明朝&quot;;">刺激剤</span></p> <p class="MsoNormal"></p> <p class="MsoNormal"><b style=""><span style= "font-family: &quot;MS 明朝&quot;;">シングレア</span></b></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">モンテルカストナトリウム</span><span lang="EN-US">montelukast sodium</span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">ロイコトリエン受容体拮抗剤</span></p> <p class="MsoNormal"></p> <p class="MsoNormal"><b style=""><span style= "font-family: &quot;MS 明朝&quot;;">クロモリン</span></b><span lang= "EN-US">�</span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">クロモグリク酸ナトリウム</span> <span lang="EN-US">sodium cromoglicate</span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">アレルギー性疾患治療剤</span></p> <p class="MsoNormal"></p> <p class="MsoNormal"><b style=""><span style= "font-family: &quot;MS 明朝&quot;;">クラリチン</span></b></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">ロラタジン</span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">持続性選択</span><span lang= "EN-US">H1-</span><span style= "font-family: &quot;MS 明朝&quot;;">受容体拮抗・アレルギー治療剤</span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">【適応】アレルギー性鼻炎,じんま疹,皮膚疾患(湿疹・皮膚炎,皮膚そう痒症)に伴うそう痒</span></p> <p class="MsoNormal"></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">プロピオン酸<b style= "">ベクロメタゾン</b></span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">副腎皮質ホルモン</span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">【適応】鼻腔内吸入用:アレルギー性鼻炎,血管運動性鼻炎</span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">ソル・メドロール</span><font face="Century"> <span lang="EN-US" style="font-size: 10pt;">=</span></font> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">メチルプレドニゾロン</span><span lang="EN-US" style="font-size: 10pt;"><br></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺性心</span><span lang="EN-US" style="font-size: 10pt;"><br></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺の障害に起因する右心負荷</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">右心不全</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">右室肥大</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺血管障害型</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺血栓・塞栓症</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">原発性肺高血圧などによる</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">換気障害型</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">: COPD,</font></span> <span style="font-size: 10pt; font-family: &quot;MS 明朝&quot;;">気管支喘息</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">睡眠時無呼吸症候群</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺線維症などによる</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">症状</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">: [</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">臨床症状</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">]</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">呼吸困難</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">胸痛</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">脳循環障害・低酸素血症・高炭酸ガス血症により脳神経症状</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">ときに失神発作</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">浮腫・腹水貯留により腹部膨満や食欲不振</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">. [</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">他覚症状</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">]</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">頸静脈怒張</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肝腫大</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">浮腫・腹水</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">三尖弁閉鎖不全が生じると肝に収縮期波動を触知</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">右室拡大が高度になると胸骨左縁が拍動的に膨隆することあり</span> <span style="font-size: 10pt;"><font face="Century"><span lang= "EN-US">(parasternal heave). IIp</span></font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">亢進し</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">S3</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">ギャロップ聴取</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺動脈駆出性雑音</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺動脈閉鎖不全による拡張期雑音</span> <span style="font-size: 10pt;"><font face="Century"><span lang="EN-US">(Graham Steell</span></font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">雑音</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">).</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">三尖弁閉鎖不全による汎収縮期雑音など聴取</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">検査</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:<br></font></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span lang="EN-US" style= "font-size: 10pt;"><font face="Century">CXR:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺動脈主幹部とその主な分枝の拡大</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span lang="EN-US" style= "font-size: 10pt;"><font face="Century">ECG:<br></font></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span lang="EN-US" style= "font-size: 10pt;"><br></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">右心カテーテル検査</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">平均肺動脈圧上昇で高い症例ほど予後不良</span> <span style="font-size: 10pt;"><font face="Century"><span lang= "EN-US">(</span></font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">判定基準は基礎疾患により異なる</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">). PCWP</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">は正常</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">治療</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">原疾患の治療に加え</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">気道感染</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">水分の過摂取</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">呼吸筋疲労などの増悪因子の除去に努める</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">栄養管理も重要</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">呼吸不全に対しては酸素投与</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">右心不全によるうっ血症状にたいしては利尿薬投与</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p align="right" class="MsoNormal" style= "margin: 0mm 0mm 0pt; text-align: right;"><span lang="EN-US" style= "font-size: 10pt;"><font face="Century">[</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">杉本</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">内科学</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">]<br></font></span></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"></p> <p class="MsoNormal" style="margin: 0mm 0mm 0pt;"></p>
<p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;; font-weight: bold;">イプラトロピウム</span> <span lang="EN-US" style="font-size: 10pt;"><font face="Century"><span style= "font-weight: bold;">ipratopium</span> (</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">アトロベント</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">Atrovent):</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">抗コリン薬</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">第四級アンモニウム</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">気管支収縮予防</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">吸入で用いられる</span> <span lang="EN-US" style="font-size: 10pt;"><font face= "Century">(</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">専用のアダプターを用いて</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">, 1</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">回</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">1-2</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">噴射</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">).</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">【適応】</span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">次の疾患の気道閉塞性障害に基づく呼吸困難など諸症状の緩解</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">気管支喘息</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">慢性気管支炎</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺気腫</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;; font-weight: bold;"><br></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;; font-weight: bold;">アルブテロール</span> <span lang="EN-US" style="font-size: 10pt; font-weight: bold;"><font face= "Century">=</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;; font-weight: bold;">サルブタモール</span> <span style="font-size: 10pt;"><font face="Century"><span lang= "EN-US"><span style="font-weight: bold;">salbutamol sulfate</span>:</span></font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">気管支拡張</span><font face="Century"><span style="font-size: 10pt;">�</span><span lang="EN-US" style="font-size: 10pt;">2-</span></font><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">刺激剤</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">【適応】錠剤・エアゾール・吸入液:次の疾患の気道閉塞性障害に基づく諸症状の緩解</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">気管支喘息</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">小児喘息</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺気腫</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">急・慢性気管支炎</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺結核</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">, [</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">錠剤は次も含む</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">]</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">ケイ肺結核</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">適応関連注意</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">[</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">エアゾール</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">]:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">喘息発作に対する対症療法剤であるので</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">本剤の使用は発作発現時に限る</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">シロップ・ドライシロップ</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">次の疾患に基づく気管支けいれんの緩解</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">気管支喘息</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">気管支炎</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">喘息様気管支炎</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">【重大な副作用】重篤な血清カリウム値の低下</span> <span lang="EN-US" style="font-size: 10pt;"><font face= "Century">(</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">頻度不明</span><font face="Century"><span lang="EN-US" style="font-size: 10pt;">):</span> <span style= "font-size: 10pt;">Beta</span><span lang="EN-US" style= "font-size: 10pt;">2-</span></font><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">刺激剤により重篤な血清カリウム値の低下が報告されている</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">また</span><font face="Century"><span lang="EN-US" style="font-size: 10pt;">,</span> <span style= "font-size: 10pt;">beta</span><span lang="EN-US" style= "font-size: 10pt;">2-</span></font><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">刺激剤による血清カリウム値の低下作用は</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">キサンチン誘導体</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">ステロイド剤及び利尿剤の併用により増強することがあるので</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">重症喘息患者では特に注意する</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">更に</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">低酸素血症は血清カリウム値の低下が心リズムに及ぼす作用を増強することがある</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">このような場合には血清カリウム値をモニターすることが望ましい</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span lang="EN-US" style= "font-size: 10pt;"><font face="Century">Definition of Shotty<br></font></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span lang="EN-US" style= "font-size: 10pt;"><font face="Century">Shotty: Resembling shot or pellets of lead, shotgun pellets and, hence, hard and round. The term "shotty" was in use in the 19th century. It is now generally obsolete but it is still in medicinal usage.<br></font></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span lang="EN-US" style= "font-size: 10pt;"><font face="Century">Shotty is very commonly used in describing the feel of lymph nodes (the lymph glands) when they are palpated (felt) through the skin. "Shotty" lymph nodes are ones that are not only hard and round but also small and surely of no consequence.<br></font></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><font face= "Century"><span lang="EN-US" style="font-size: 10pt;">No consequence is not always the case with shotty. The pustules (the little pockets of pus) in smallpox are said to feel shotty, according to D.A. Henderson, the director of the World Health Organization (WHO) Smallpox Eradication Unit from its inception in 1966 to 1977. "Smallpox pustules have a dimple, a dent in the center. Doctors say that the pustules have a 'shotty' feel, like shotgun pellets. You can roll them between your fingertips under the skin,"</span> <span lang="EN-US" style="font-size: 10pt;">Henderson</span> <span lang="EN-US" style="font-size: 10pt;">recounted (quoted by Richard Preston in The New Yorker,</span> <span lang="EN-US" style="font-size: 10pt;">July 12, 1999</span><span lang="EN-US" style="font-size: 10pt;">).<br></span></font></p> <p align="right" style="margin: 0mm 0mm 0pt; text-align: right;" class= "MsoNormal"><span lang="EN-US" style="font-size: 10pt;"><font face= "Century">[MedicineNet]<br></font></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"></p> <p class="MsoNormal"><b style=""><span style= "font-family: &quot;MS 明朝&quot;;">フルニソリド</span></b></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">副腎皮質ホルモン</span> <span style="font-family: &quot;MS 明朝&quot;;">点鼻液</span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">【適応】アレルギー性鼻炎,血管運動性鼻炎</span></p> <p class="MsoNormal"></p> <p class="MsoNormal"><b style=""><span style= "font-family: &quot;MS 明朝&quot;;">セレベント</span></b></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">キシナホ酸サルメテロール</span><span lang="EN-US">salmeterol xinafoate</span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">長時間作動型気管支拡張</span><span style="">�</span><span lang="EN-US">2-</span><span style="font-family: &quot;MS 明朝&quot;;">刺激剤</span></p> <p class="MsoNormal"></p> <p class="MsoNormal"><b style=""><span style= "font-family: &quot;MS 明朝&quot;;">シングレア</span></b></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">モンテルカストナトリウム</span><span lang="EN-US">montelukast sodium</span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">ロイコトリエン受容体拮抗剤</span></p> <p class="MsoNormal"></p> <p class="MsoNormal"><b style=""><span style= "font-family: &quot;MS 明朝&quot;;">クロモリン</span></b></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">クロモグリク酸ナトリウム</span> <span lang="EN-US">sodium cromoglicate</span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">アレルギー性疾患治療剤</span></p> <p class="MsoNormal"></p> <p class="MsoNormal"><b style=""><span style= "font-family: &quot;MS 明朝&quot;;">クラリチン</span></b></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">ロラタジン</span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">持続性選択</span><span lang= "EN-US">H1-</span><span style= "font-family: &quot;MS 明朝&quot;;">受容体拮抗・アレルギー治療剤</span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">【適応】アレルギー性鼻炎,じんま疹,皮膚疾患(湿疹・皮膚炎,皮膚そう痒症)に伴うそう痒</span></p> <p class="MsoNormal"></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">プロピオン酸<b style= "">ベクロメタゾン</b></span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">副腎皮質ホルモン</span></p> <p class="MsoNormal"><span style= "font-family: &quot;MS 明朝&quot;;">【適応】鼻腔内吸入用:アレルギー性鼻炎,血管運動性鼻炎</span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">ソル・メドロール</span><font face="Century"><span lang="EN-US" style="font-size: 10pt;">=</span></font> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">メチルプレドニゾロン</span><span lang="EN-US" style="font-size: 10pt;"><br></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺性心</span><span lang="EN-US" style="font-size: 10pt;"><br></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺の障害に起因する右心負荷</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">右心不全</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">右室肥大</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺血管障害型</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺血栓・塞栓症</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">原発性肺高血圧などによる</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">換気障害型</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">: COPD,</font></span> <span style="font-size: 10pt; font-family: &quot;MS 明朝&quot;;">気管支喘息</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">睡眠時無呼吸症候群</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺線維症などによる</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">症状</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">: [</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">臨床症状</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">]</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">呼吸困難</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">胸痛</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">脳循環障害・低酸素血症・高炭酸ガス血症により脳神経症状</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">ときに失神発作</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">浮腫・腹水貯留により腹部膨満や食欲不振</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">. [</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">他覚症状</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">]</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">頸静脈怒張</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肝腫大</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">浮腫・腹水</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">三尖弁閉鎖不全が生じると肝に収縮期波動を触知</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">右室拡大が高度になると胸骨左縁が拍動的に膨隆することあり</span> <span style="font-size: 10pt;"><font face="Century"><span lang= "EN-US">(parasternal heave). IIp</span></font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">亢進し</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">S3</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">ギャロップ聴取</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺動脈駆出性雑音</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺動脈閉鎖不全による拡張期雑音</span> <span style="font-size: 10pt;"><font face="Century"><span lang="EN-US">(Graham Steell</span></font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">雑音</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">).</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">三尖弁閉鎖不全による汎収縮期雑音など聴取</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">検査</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:<br></font></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span lang="EN-US" style= "font-size: 10pt;"><font face="Century">CXR:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">肺動脈主幹部とその主な分枝の拡大</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span lang="EN-US" style= "font-size: 10pt;"><font face="Century">ECG:<br></font></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span lang="EN-US" style= "font-size: 10pt;"><br></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">右心カテーテル検査</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">平均肺動脈圧上昇で高い症例ほど予後不良</span> <span style="font-size: 10pt;"><font face="Century"><span lang= "EN-US">(</span></font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">判定基準は基礎疾患により異なる</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">). PCWP</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">は正常</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">治療</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">原疾患の治療に加え</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">気道感染</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">水分の過摂取</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">呼吸筋疲労などの増悪因子の除去に努める</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">栄養管理も重要</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">呼吸不全に対しては酸素投与</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">,</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">右心不全によるうっ血症状にたいしては利尿薬投与</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">.<br></font></span></p> <p align="right" style="margin: 0mm 0mm 0pt; text-align: right;" class= "MsoNormal"><span lang="EN-US" style="font-size: 10pt;"><font face= "Century">[</font></span><span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">杉本</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">:</font></span> <span style= "font-size: 10pt; font-family: &quot;MS 明朝&quot;;">内科学</span><span lang="EN-US" style="font-size: 10pt;"><font face="Century">]<br></font></span></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"></p> <p style="margin: 0mm 0mm 0pt;" class="MsoNormal"></p>

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